| Regulatory reference: | According to ASTM ASTM E1173 – 15. |
| Claim: | Effectiveness of alcohol swabs |
| Application field: | Finished products. |
| Description of the test: | The test method is designed to measure the reduction of the microflora of the skin for Preinjection Skin Preparations. This test method is conducted on human subjects selected randomly from a group of subjects who, after refraining voluntarily from using topical and oral antimicrobials for at least two weeks (14 days), exhibit acceptably high normal flora counts on the skin sites to be used in testing. |
| Regulatory reference: | According to ASTM E2315 – 16. |
| Claim: | Kills 99.99% of germs |
| Application field: | Finished products. |
| Description of the test: | Antimicrobial activity of specific materials is measured with this technique by measuring the changes in a population of aerobic microorganisms within a specified sampling time. This test can be used in particular for the hand sanitizers with the claim “kills 99.99% of germs”. |
| Regulatory reference: | According to OECD 456. |
| Claim: | No endocrin disruption |
| Application field: | Raw ingredients and finished products. |
| Description of the test: | The purpose of the test is identifying substances that interfere with 17-ß estradiol and testosterone production. |
| Regulatory reference: | Proprietary method |
| Claim: | Improves healing process |
| Application field: | Wound healing products. |
| Description of the test: | Analysis of the regenerative efficacy on epidermal cell cultures after simulated wounding. Results in terms of percentage of improvement in the regeneration kinetics versus untreated substrate. |
| Regulatory reference: | Proprietary method |
| Claim: | Mucoadhesive effect |
| Application field: | Finished products for direct application on external mucosae. |
| Description of the test: | Gravimetric analysis of the adhesion of a product on a layer of mucin against the same product on an untreated plane. Detachment kinetics in terms of percentage of adhesion against a non-adhesive control. |
| Regulatory reference: | Proprietary method |
| Claim: | Saliva resistant |
| Application field: | Finished products for oral application. |
| Description of the test: | Analysis of the resistance to washing off by artificial saliva by gravimetric analysis of the dry weight of the sample before and after washes in controlled conditions. |